Lipo-C

Lipo-C

Lipo-C is a compound consisting of L-carnitine linked to a lipophilic group, under investigation for potential effects on cellular fatty acid transport, mitochondrial β-oxidation processes, and metabolic energy management. Laboratory models are used to study Lipo-C's capacity to enhance mitochondrial fatty acid absorption, promote lipid turnover, and adjust metabolic substrate selection under energetically demanding conditions.

Scientific research examines how Lipo-C impacts long-chain acyl-CoA translocation into mitochondria, mitochondrial respiratory chain performance, and consequent effects on lipid storage and cellular energy balance.

Lipo-C Introduction

Lipo-C serves in scientific settings for evaluating metabolic-endocrine control of lipolysis, fatty acid oxidation, adipocyte metabolic activity, and mitochondrial biogenesis. Researchers additionally investigate its potential effects on systemic lipid concentrations, visceral fat accumulation, and energy expenditure changes during experimental dietary challenges or insulin-resistance models.

Lipo-C Chemical Properties

Lipo-C is produced from L-carnitine esterified with a lipophilic group, designed to optimize cellular uptake and mitochondrial targeting. Given that structural derivation may vary, a single definitive molecular formula is not listed. Analytical identity and purity have been confirmed for this batch.

• Observed Mass (MS): 711.9 Da
• Purity (HPLC): 99.42%
• Batch Number: 2025007
• Primary Retention Time: 3.48 min
• Instrument: LCMS-7800 Series (Calibrated)
• Analytical Note: Primary peak confirmed by mass and retention time; trace secondary peak area 0.58%

Lipo-C Scientific Investigation

Lipo-C and Fatty Acid Metabolic Processes

Experimental research has explored the capacity of Lipo-C, an L-carnitine–derived compound, to facilitate mitochondrial transport of long-chain fatty acids and improve their oxidative utilization. These studies suggest that by promoting efficient fatty acid entry into mitochondria, Lipo-C may enhance overall cellular energy production and metabolic efficiency under substrate-enriched experimental conditions.

Lipo-C and Cellular Bioenergetics

Additional research concentrates on Lipo-C's potential to promote lipolytic activity within adipocytes, resulting in elevated free fatty acid turnover and decreased intracellular triglyceride storage. Research also investigates its influence on mitochondrial biogenesis through activation of regulatory pathways such as PGC-1α, which controls oxidative enzyme expression and energy metabolism. Together, these findings establish a basis for studying Lipo-C's potential applications in metabolic health—particularly its impact on visceral fat reduction, hepatic lipid homeostasis, and insulin sensitivity—though its use remains strictly limited to controlled laboratory research by qualified professionals.

The Lipo-C research compound is designated exclusively for controlled experimental and investigative purposes within certified laboratory environments. It is to be handled and utilized only by trained and qualified research professionals equipped to conduct studies involving biochemical or metabolic compounds. This material is strictly prohibited for human or veterinary use, including any form of therapeutic, diagnostic, or clinical administration. Its distribution and application are intended to support scientific inquiry and laboratory-based discovery under proper institutional oversight.

Document Compiler

This review was authored, assembled, and organized by Dr. Charles Hoppel, Ph.D.

Dr. Hoppel is an esteemed biochemist best recognized for his pioneering contributions to mitochondrial energy metabolism research and the biochemical roles of L-carnitine in fatty acid oxidation. Throughout his career, his investigations have substantially enhanced scientific understanding of mitochondrial transport mechanisms, metabolic control, and the processes governing carnitine-dependent β-oxidation under both normal and disease conditions.

Scientific Research Author

Dr. Charles Hoppel has conducted comprehensive investigations into carnitine metabolism and its influence on mitochondrial bioenergetics, emphasizing its role in fatty acid transport, oxidative enzyme function, and cellular energy equilibrium. His work—together with that of colleagues including W.C. Stanley, C.J. Rebouche, L.L. Jones, and R. Ringseis—has been essential in clarifying the biochemical and physiological pathways involving L-carnitine and related compounds. Collectively, their studies provide the scientific foundation supporting current experimental research into Lipo-C and similar metabolic formulations.

Dr. Hoppel and his collaborators are recognized for their substantial contributions to advancing understanding of carnitine metabolism and mitochondrial function. This recognition serves solely to credit the scientific research of Dr. Hoppel and his colleagues. It does not suggest any endorsement or association with this product. Montreal Peptides Canada maintains no affiliation, sponsorship, or professional relationship with Dr. Hoppel or any referenced researchers.

Reference Citations

Stanley WC, et al. Regulation of mitochondrial fatty acid oxidation by l-carnitine. J Mol Cell Cardiol. 1999;31(10):1435-1448. PMID: 10502507.

Rebouche CJ. Carnitine function and requirements during the life cycle. Fetal Pediatr Pathol. 2004;23(1-2):99-114. PMID: 15362046.

Jones LL, et al. Role of l-carnitine in cardiovascular disease. Cardiovasc Res. 1999;42(2):219-223. PMID: 10364221.

Hoppel C. The role of carnitine in normal and altered fatty acid metabolism. Am J Kidney Dis. 2003;41(4 Suppl 4):S4-12. PMID: 12664513.

Ringseis R, et al. Carnitine transport and mitochondrial metabolism. Biochim Biophys Acta. 2014;1842(9):1282–1293. PMID: 24950924.

ClinicalTrials.gov Identifier: NCT01376341. L-carnitine derivative supplementation in metabolic syndrome research.

ClinicalTrials.gov Identifier: NCT02410932. Mitochondrial fatty acid oxidation enhancement in human research settings.